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Elucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomics

The identification of the modes of action of bioactive compounds is a major challenge in chemical systems biology of diseases. Genome-wide expression profiling of transcriptional responses to compound treatment for human cell lines is a promising unbiased approach for the mode-of-action analysis. He...

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Detalles Bibliográficos
Autores principales:	Iwata, Michio, Sawada, Ryusuke, Iwata, Hiroaki, Kotera, Masaaki, Yamanishi, Yoshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223214/ https://www.ncbi.nlm.nih.gov/pubmed/28071740 http://dx.doi.org/10.1038/srep40164

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