Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding

The global outbreak of SARS in 2002-2003 was caused by the infection of a new human coronavirus SARS-CoV. The infection of SARS-CoV is mediated mainly through the viral surface glycoproteins, which consist of S1 and S2 subunits and form trimer spikes on the envelope of the virions. Here we report th...

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Detalles Bibliográficos
Autores principales: Gui, Miao, Song, Wenfei, Zhou, Haixia, Xu, Jingwei, Chen, Silian, Xiang, Ye, Wang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223232/
https://www.ncbi.nlm.nih.gov/pubmed/28008928
http://dx.doi.org/10.1038/cr.2016.152

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