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Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche

BACKGROUND: Leukemic and mesenchymal stem cells interact in the leukemic microenvironment and affect each other differently. This interplay has also important implications for the hematopoietic stem cell (HSC) biology and function. This study evaluated human HSC self-renewal potential and quiescence...

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Detalles Bibliográficos
Autores principales:	Vanegas, Natalia-Del Pilar, Vernot, Jean-Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223333/ https://www.ncbi.nlm.nih.gov/pubmed/28078190 http://dx.doi.org/10.1186/s40164-016-0062-1

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