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Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?

Recent studies have demonstrated that the bacterial chaperone and serine protease high temperature requirement A (HtrA) is closely associated with the establishment and progression of several infectious diseases. HtrA activity enhances bacterial survival under stress conditions, but also has direct...

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Detalles Bibliográficos
Autores principales: Wessler, Silja, Schneider, Gisbert, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223389/
https://www.ncbi.nlm.nih.gov/pubmed/28069057
http://dx.doi.org/10.1186/s12964-017-0162-5