Absence of in vivo selection for K13 mutations after artemether–lumefantrine treatment in Uganda

BACKGROUND: Individual drug treatment may select resistant parasites in the human body, a process termed in vivo selection. Some single nucleotide polymorphisms in Plasmodium falciparum chloroquine-resistance transporter (pfcrt) and multidrug resistance gene 1 (pfmdr1) genes have been reportedly sel...

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Detalles Bibliográficos
Autores principales: Balikagala, Betty, Mita, Toshihiro, Ikeda, Mie, Sakurai, Miki, Yatsushiro, Shouki, Takahashi, Nobuyuki, Tachibana, Shin-Ichiro, Auma, Mary, Ntege, Edward H., Ito, Daisuke, Takashima, Eizo, Palacpac, Nirianne Marie Q., Egwang, Thomas G., Onen, Joseph Okello, Kataoka, Masatoshi, Kimura, Eisaku, Horii, Toshihiro, Tsuboi, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223472/
https://www.ncbi.nlm.nih.gov/pubmed/28068997
http://dx.doi.org/10.1186/s12936-016-1663-1

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