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The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition

Long interspersed elements 1 (L1) are active mobile elements that constitute almost 17% of the human genome. They amplify through a “copy-and-paste” mechanism termed retrotransposition, and de novo insertions related to these elements have been reported to cause 0.2% of genetic diseases. Our previou...

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Detalles Bibliográficos
Autores principales:	Servant, Geraldine, Streva, Vincent A., Derbes, Rebecca S., Wijetunge, Madushani I., Neeland, Marc, White, Travis B., Belancio, Victoria P., Roy-Engel, Astrid M., Deininger, Prescott L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223499/ https://www.ncbi.nlm.nih.gov/pubmed/28049704 http://dx.doi.org/10.1534/genetics.116.188680

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