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Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness
BACKGROUND: Glioblastoma is an untreatable brain cancer. The tumors contain a population of stem-like cells which are highly invasive and resistant to therapies. These cells are the main reason for the lethality of glioblastoma. Extracellular guidance molecule netrin-1 promotes the invasiveness and...
Autores principales: | Ylivinkka, Irene, Sihto, Harri, Tynninen, Olli, Hu, Yizhou, Laakso, Aki, Kivisaari, Riku, Laakkonen, Pirjo, Keski-Oja, Jorma, Hyytiäinen, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223529/ https://www.ncbi.nlm.nih.gov/pubmed/28069038 http://dx.doi.org/10.1186/s13046-016-0482-0 |
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