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A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib
Semaphorins comprise a large family of ligands that regulate key cellular functions through their receptors, plexins. In this study, we show that the transmembrane semaphorin 4A (Sema4A) can also function as a receptor, rather than a ligand, and transduce signals triggered by the binding of Plexin-B...
Autores principales: | Sun, Tianliang, Yang, Lida, Kaur, Harmandeep, Pestel, Jenny, Looso, Mario, Nolte, Hendrik, Krasel, Cornelius, Heil, Daniel, Krishnan, Ramesh K., Santoni, Marie-Josée, Borg, Jean-Paul, Bünemann, Moritz, Offermanns, Stefan, Swiercz, Jakub M., Worzfeld, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223600/ https://www.ncbi.nlm.nih.gov/pubmed/28007914 http://dx.doi.org/10.1083/jcb.201602002 |
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