Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO

Podosomes represent a class of integrin-mediated cell-matrix adhesions formed by migrating and matrix-degrading cells. We demonstrate that in macrophage-like THP1 cells and fibroblasts stimulated to produce podosomes, down-regulation of the G-protein ARF1 or the ARF1 guanine nucleotide exchange fact...

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Detalles Bibliográficos
Autores principales: Rafiq, Nisha Bte Mohd, Lieu, Zi Zhao, Jiang, Tingting, Yu, Cheng-han, Matsudaira, Paul, Jones, Gareth E., Bershadsky, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223603/
https://www.ncbi.nlm.nih.gov/pubmed/28007915
http://dx.doi.org/10.1083/jcb.201605104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223603/
https://www.ncbi.nlm.nih.gov/pubmed/28007915
http://dx.doi.org/10.1083/jcb.201605104

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