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Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol

INTRODUCTION: There is no curative treatment available for patients with chemotherapy relapsed or refractory CD19+ B cells-derived acute lymphoblastic leukaemia (r/r B-ALL). Although CD19-targeting second-generation (2nd-G) chimeric antigen receptor (CAR)-modified T cells carrying CD28 or 4-1BB doma...

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Detalles Bibliográficos
Autores principales:	Tang, Xiao-Yi, Sun, Yao, Zhang, Ang, Hu, Guo-Liang, Cao, Wei, Wang, Dan-Hong, Zhang, Bin, Chen, Hu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Haematology (Incl Blood Transfusion)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223707/ https://www.ncbi.nlm.nih.gov/pubmed/28039295 http://dx.doi.org/10.1136/bmjopen-2016-013904

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