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Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil

With the urbanisation of the population in developing countries and the process of globalisation, Chagas has become an emerging disease in the urban areas of endemic and non-endemic countries. In 2006, it was estimated that the prevalence of Chagas disease among the general Bolivian population was 6...

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Autores principales: Luna, Expedito JA, Furucho, Celia R, Silva, Rubens A, Wanderley, Dalva M, Carvalho, Noemia B, Satolo, Camila G, Leite, Ruth M, Silveira, Cassio, Silva, Lia MB, Aith, Fernando M, Carneiro, Nivaldo, Shikanai-Yasuda, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224353/
https://www.ncbi.nlm.nih.gov/pubmed/27849221
http://dx.doi.org/10.1590/0074-02760160384
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author Luna, Expedito JA
Furucho, Celia R
Silva, Rubens A
Wanderley, Dalva M
Carvalho, Noemia B
Satolo, Camila G
Leite, Ruth M
Silveira, Cassio
Silva, Lia MB
Aith, Fernando M
Carneiro, Nivaldo
Shikanai-Yasuda, Maria A
author_facet Luna, Expedito JA
Furucho, Celia R
Silva, Rubens A
Wanderley, Dalva M
Carvalho, Noemia B
Satolo, Camila G
Leite, Ruth M
Silveira, Cassio
Silva, Lia MB
Aith, Fernando M
Carneiro, Nivaldo
Shikanai-Yasuda, Maria A
author_sort Luna, Expedito JA
collection PubMed
description With the urbanisation of the population in developing countries and the process of globalisation, Chagas has become an emerging disease in the urban areas of endemic and non-endemic countries. In 2006, it was estimated that the prevalence of Chagas disease among the general Bolivian population was 6.8%. The aim of the present study was to determine the prevalence of Trypanosoma cruzi infection among Bolivian immigrants living in São Paulo, Brazil. This study had a sample of 633 volunteers who were randomly selected from the clientele of primary care units located in the central districts of São Paulo, Brazil. Infection was detected by two different ELISA assays with epimastigote antigens, followed by an immunoblot with trypomastigote antigens as a confirmatory test. The prevalence of the infection was 4.4%. Risk factors independently associated with the infection were: a history of rural jobs in Bolivia, knowledge of the vector involved in transmission, and having relatives with Chagas disease. Brazil has successfully eliminated household vector transmission of T. cruzi, as well as its transmission by blood transfusion. The arrival of infected immigrants represents an additional challenge to primary care clinics to manage chronic Chagas disease, its vertical transmission, and the blood derivatives and organ transplant programs.
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spelling pubmed-52243532017-01-13 Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil Luna, Expedito JA Furucho, Celia R Silva, Rubens A Wanderley, Dalva M Carvalho, Noemia B Satolo, Camila G Leite, Ruth M Silveira, Cassio Silva, Lia MB Aith, Fernando M Carneiro, Nivaldo Shikanai-Yasuda, Maria A Mem Inst Oswaldo Cruz Articles With the urbanisation of the population in developing countries and the process of globalisation, Chagas has become an emerging disease in the urban areas of endemic and non-endemic countries. In 2006, it was estimated that the prevalence of Chagas disease among the general Bolivian population was 6.8%. The aim of the present study was to determine the prevalence of Trypanosoma cruzi infection among Bolivian immigrants living in São Paulo, Brazil. This study had a sample of 633 volunteers who were randomly selected from the clientele of primary care units located in the central districts of São Paulo, Brazil. Infection was detected by two different ELISA assays with epimastigote antigens, followed by an immunoblot with trypomastigote antigens as a confirmatory test. The prevalence of the infection was 4.4%. Risk factors independently associated with the infection were: a history of rural jobs in Bolivia, knowledge of the vector involved in transmission, and having relatives with Chagas disease. Brazil has successfully eliminated household vector transmission of T. cruzi, as well as its transmission by blood transfusion. The arrival of infected immigrants represents an additional challenge to primary care clinics to manage chronic Chagas disease, its vertical transmission, and the blood derivatives and organ transplant programs. Instituto Oswaldo Cruz, Ministério da Saúde 2016-11-16 2017-01 /pmc/articles/PMC5224353/ /pubmed/27849221 http://dx.doi.org/10.1590/0074-02760160384 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Luna, Expedito JA
Furucho, Celia R
Silva, Rubens A
Wanderley, Dalva M
Carvalho, Noemia B
Satolo, Camila G
Leite, Ruth M
Silveira, Cassio
Silva, Lia MB
Aith, Fernando M
Carneiro, Nivaldo
Shikanai-Yasuda, Maria A
Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil
title Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil
title_full Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil
title_fullStr Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil
title_full_unstemmed Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil
title_short Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil
title_sort prevalence of trypanosoma cruzi infection among bolivian immigrants in the city of são paulo, brazil
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224353/
https://www.ncbi.nlm.nih.gov/pubmed/27849221
http://dx.doi.org/10.1590/0074-02760160384
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