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A genome wide dosage suppressor network reveals genomic robustness

Genomic robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of genomic robustness in budding yeast by genome wide dosage suppressor analysis of 53 conditional lethal mutations in cell division cycle and RNA synthesis rel...

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Detalles Bibliográficos
Autores principales: Patra, Biranchi, Kon, Yoshiko, Yadav, Gitanjali, Sevold, Anthony W., Frumkin, Jesse P., Vallabhajosyula, Ravishankar R., Hintze, Arend, Østman, Bjørn, Schossau, Jory, Bhan, Ashish, Marzolf, Bruz, Tamashiro, Jenna K., Kaur, Amardeep, Baliga, Nitin S., Grayhack, Elizabeth J., Adami, Christoph, Galas, David J., Raval, Alpan, Phizicky, Eric M., Ray, Animesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224485/
https://www.ncbi.nlm.nih.gov/pubmed/27899637
http://dx.doi.org/10.1093/nar/gkw1148