Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion

The 2-methylthio (ms(2)) modification at A37 of tRNAs is critical for accurate decoding, and contributes to metabolic homeostasis in mammals. However, the regulatory mechanism of ms(2) modification remains largely unknown. Here, we report that cysteine hydropersulfide (CysSSH), a newly identified re...

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Detalles Bibliográficos
Autores principales: Takahashi, Nozomu, Wei, Fan-Yan, Watanabe, Sayaka, Hirayama, Mayumi, Ohuchi, Yuya, Fujimura, Atsushi, Kaitsuka, Taku, Ishii, Isao, Sawa, Tomohiro, Nakayama, Hideki, Akaike, Takaaki, Tomizawa, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224495/
https://www.ncbi.nlm.nih.gov/pubmed/27568003
http://dx.doi.org/10.1093/nar/gkw745

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