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A double-strand break can trigger immunoglobulin gene conversion

All three B cell-specific activities of the immunoglobulin (Ig) gene re-modeling system—gene conversion, somatic hypermutation and class switch recombination—require activation-induced deaminase (AID). AID-induced DNA lesions must be further processed and dissected into different DNA recombination p...

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Detalles Bibliográficos
Autores principales:	Bastianello, Giulia, Arakawa, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224512/ https://www.ncbi.nlm.nih.gov/pubmed/27701075 http://dx.doi.org/10.1093/nar/gkw887

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