Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions

RecA-family recombinase-catalyzed ATP-dependent homologous joint formation is critical for homologous recombination, in which RecA or Rad51 binds first to single-stranded (ss)DNA and then interacts with double-stranded (ds)DNA. However, when RecA or Rad51 interacts with dsDNA before binding to ssDNA...

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Detalles Bibliográficos
Autores principales: Konomura, Naoto, Arai, Naoto, Shinohara, Takeshi, Kobayashi, Jun, Iwasaki, Wakana, Ikawa, Shukuko, Kusano, Kohji, Shibata, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224515/
https://www.ncbi.nlm.nih.gov/pubmed/27794044
http://dx.doi.org/10.1093/nar/gkw998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224515/
https://www.ncbi.nlm.nih.gov/pubmed/27794044
http://dx.doi.org/10.1093/nar/gkw998

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