Hydrophobic mismatch demonstrated for membranolytic peptides, and their use as molecular rulers to measure bilayer thickness in native cells

Hydrophobic mismatch is a well-recognized principle in the interaction of transmembrane proteins with lipid bilayers. This concept was extended here to amphipathic membranolytic α-helices. Nine peptides with lengths between 14 and 28 amino acids were designed from repeated KIAGKIA motifs, and their...

Descripción completa

Detalles Bibliográficos
Autores principales: Grau-Campistany, Ariadna, Strandberg, Erik, Wadhwani, Parvesh, Reichert, Johannes, Bürck, Jochen, Rabanal, Francesc, Ulrich, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224518/
https://www.ncbi.nlm.nih.gov/pubmed/25807192
http://dx.doi.org/10.1038/srep09388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224518/
https://www.ncbi.nlm.nih.gov/pubmed/25807192
http://dx.doi.org/10.1038/srep09388

Ejemplares similares