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Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis
BACKGROUND: Artemisinin-based combination therapies (ACTs) are the mainstay of the current treatment of uncomplicated Plasmodium falciparum malaria, but ACT resistance is spreading across Southeast Asia. Dihydroartemisinin-piperaquine is one of the five ACTs currently recommended by the World Health...
Autores principales: | Hoglund, Richard M., Workman, Lesley, Edstein, Michael D., Thanh, Nguyen Xuan, Quang, Nguyen Ngoc, Zongo, Issaka, Ouedraogo, Jean Bosco, Borrmann, Steffen, Mwai, Leah, Nsanzabana, Christian, Price, Ric N., Dahal, Prabin, Sambol, Nancy C., Parikh, Sunil, Nosten, Francois, Ashley, Elizabeth A., Phyo, Aung Pyae, Lwin, Khin Maung, McGready, Rose, Day, Nicholas P. J., Guerin, Philippe J., White, Nicholas J., Barnes, Karen I., Tarning, Joel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224788/ https://www.ncbi.nlm.nih.gov/pubmed/28072872 http://dx.doi.org/10.1371/journal.pmed.1002212 |
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