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Pregnane X receptors regulate CYP2C8 and P‐glycoprotein to impact on the resistance of NSCLC cells to Taxol

Cytochrome P450 2C8 (CYP2C8) is one of the enzymes that primarily participate in producing metabolisms of medications and P‐glycoprotein (P‐gp) has been regarded as one of the important molecules in chemotherapeutically induced multidrug resistance (MDR). In addition, the pregnane X receptor (PXR) i...

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Detalles Bibliográficos
Autores principales:	Chen, Yan, Huang, Wandan, Chen, Feiyu, Hu, Guoping, Li, Fenglei, Li, Jianhua, Xuan, Aiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224856/ https://www.ncbi.nlm.nih.gov/pubmed/27878971 http://dx.doi.org/10.1002/cam4.960

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