Cargando…

Association Study with 77 SNPs Confirms the Robust Role for the rs10830963/G of MTNR1B Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus Development

CONTEXT: Genetic variation in human maternal DNA contributes to the susceptibility for development of gestational diabetes mellitus (GDM). OBJECTIVE: We assessed 77 maternal single nucleotide gene polymorphisms (SNPs) for associations with GDM or plasma glucose levels at OGTT in pregnancy. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rosta, Klara, Al-Aissa, Zahra, Hadarits, Orsolya, Harreiter, Jürgen, Nádasdi, Ákos, Kelemen, Fanni, Bancher-Todesca, Dagmar, Komlósi, Zsolt, Németh, László, Rigó, János, Sziller, István, Somogyi, Anikó, Kautzky-Willer, Alexandra, Firneisz, Gábor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224877/ https://www.ncbi.nlm.nih.gov/pubmed/28072873 http://dx.doi.org/10.1371/journal.pone.0169781

Ejemplares similares

The MTNR1B rs10830963 Variant in Interaction with Pre-Pregnancy BMI is a Pharmacogenetic Marker for the Initiation of Antenatal Insulin Therapy in Gestational Diabetes Mellitus
por: Firneisz, Gábor, et al.
Publicado: (2018)

Identification and Potential Clinical Utility of the MTNR1B rs10830963 Core Gene Variant Associated to Endophenotypes in Gestational Diabetes Mellitus
por: Firneisz, Gábor, et al.
Publicado: (2020)

Comments on: A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus
por: Rosta, Klara, et al.
Publicado: (2020)

Increased Proportion of Hematopoietic Stem and Progenitor Cell Population in Cord Blood of Neonates Born to Mothers with Gestational Diabetes Mellitus
por: Hadarits, Orsolya, et al.
Publicado: (2016)

PNPLA3 rs738409 risk genotype decouples TyG index from HOMA2-IR and intrahepatic lipid content
por: Nádasdi, Ákos, et al.
Publicado: (2023)

Altered Immune Regulation in Type 1 Diabetes
por: Zóka, András, et al.
Publicado: (2013)

CTRP-1 levels are related to insulin resistance in pregnancy and gestational diabetes mellitus
por: Deischinger, Carola, et al.
Publicado: (2020)

Secretagogin is Related to Insulin Secretion but Unrelated to Gestational Diabetes Mellitus Status in Pregnancy
por: Deischinger, Carola, et al.
Publicado: (2020)

Combined effect of pancreatic lipid content and gene variants (TCF7L2, WFS1 and 11BHSD1) on B-cell function in Middle Aged Women in a Post Hoc Analysis
por: Nádasdi, Ákos, et al.
Publicado: (2022)

The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics
por: Vejrazkova, Daniela, et al.
Publicado: (2022)

Gremlin-1 in pregnancy and postpartum: relation to the fatty liver index, markers of bone health, glucose metabolism and gestational diabetes mellitus status
por: Deischinger, Carola, et al.
Publicado: (2023)

The Association between Dietary Iron Intake, SNP of the MTNR1B rs10830963, and Glucose Metabolism in Chinese Population
por: Shen, Liping, et al.
Publicado: (2023)

Increased Risk of Myocardial Infarction Among Patients With Type 2 Diabetes Who Carry the Common rs10830963 Variant in the MTNR1B Gene
por: Tan, Xiao, et al.
Publicado: (2020)

Management of Pregnant Women after Bariatric Surgery
por: Harreiter, Jürgen, et al.
Publicado: (2018)

Changes in Serum Lipid Levels During Pregnancy in Type 1 and Type 2 Diabetic Subjects
por: Göbl, Christian S., et al.
Publicado: (2010)

Evaluation of the effect of MTNR1B rs10830963 gene variant on the therapeutic efficacy of nateglinide in treating type 2 diabetes among Chinese Han patients
por: Song, Jin-Fang, et al.
Publicado: (2021)

MTNR1B rs10830963 is associated with fasting plasma glucose, HbA(1C )and impaired beta-cell function in Chinese Hans from Shanghai
por: Liu, Chen, et al.
Publicado: (2010)

Is vaginal progesterone treatment associated with the development of gestational diabetes? A retrospective case–control study
por: Rosta, Klara, et al.
Publicado: (2018)

Sex and Gender Differences in Prevention of Type 2 Diabetes
por: Harreiter, Jürgen, et al.
Publicado: (2018)

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
por: Kautzky-Willer, Alexandra, et al.
Publicado: (2016)

Correction to: Sex differences in type 2 diabetes
por: Kautzky-Willer, Alexandra, et al.
Publicado: (2023)

Sex differences in type 2 diabetes
por: Kautzky-Willer, Alexandra, et al.
Publicado: (2023)

G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release: Studies Involving 19,605 Europeans
por: Sparsø, Thomas, et al.
Publicado: (2009)

Polymorphisms in Four Genes (KCNQ1 rs151290, KLF14 rs972283, GCKR rs780094 and MTNR1B rs10830963) and Their Correlation with Type 2 Diabetes Mellitus in Han Chinese in Henan Province, China
por: Gao, Kaiping, et al.
Publicado: (2016)

Do Women with Diabetes Need More Intensive Action for Cardiovascular Reduction than Men with Diabetes?
por: Harreiter, Jürgen, et al.
Publicado: (2020)

Gestational Diabetes Mellitus (GDM) – Diagnosis, Treatment and Follow-Up. Guideline of the DDG and DGGG (S3 Level, AWMF Registry Number 057/008, February 2018)
por: Schäfer-Graf, Ute Margaretha, et al.
Publicado: (2018)

Gravidität bei vorbestehendem Diabetes (Update 2023)
por: Kautzky-Willer, Alexandra, et al.
Publicado: (2023)

SUN-639 Secretagogin Levels Are Unrelated to Gestational Diabetes Mellitus in a Cohort of Pregnant Women
por: Deischinger, Carola, et al.
Publicado: (2020)

Myocardial Infarction Susceptibility and the MTNR1B Polymorphisms
por: Škrlec, Ivana, et al.
Publicado: (2023)

Lipoprotein(a) is not related to markers of insulin resistance in pregnancy
por: Todoric, Jelena, et al.
Publicado: (2013)

Lower serum chromogranin B level is associated with type 1 diabetes and with type 2 diabetes patients with intensive conservative insulin treatment
por: Herold, Zoltan, et al.
Publicado: (2020)

Glypican-4 in pregnancy and its relation to glucose metabolism, insulin resistance and gestational diabetes mellitus status
por: Deischinger, Carola, et al.
Publicado: (2021)

Reduced GLP-1 response to a meal is associated with the CTLA4 rs3087243 G/G genotype
por: Zóka, András, et al.
Publicado: (2019)

Geschlechtsspezifische Aspekte bei Prädiabetes und Diabetes mellitus – klinische Empfehlungen (Update 2023)
por: Kautzky-Willer, Alexandra, et al.
Publicado: (2023)

Histopathological Chromogranin A-Positivity Is Associated with Right-Sided Colorectal Cancers and Worse Prognosis
por: Herold, Zoltan, et al.
Publicado: (2020)

Written Briefing and Oral Counseling Increase the Willingness to Receive the SARS-CoV-2 Vaccination among Women in Puerperium: A Qualitative Prospective Cohort Study
por: Schirwani, Nawa, et al.
Publicado: (2022)

Role of Air Pollution and rs10830963 Polymorphism on the Incidence of Type 2 Diabetes: Tehran Cardiometabolic Genetic Study
por: Jabbari, Fatemeh, et al.
Publicado: (2020)

A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus
por: Huang, Bo, et al.
Publicado: (2019)

Effects of Lactobacillus rhamnosus DSM7133 on Intestinal Porcine Epithelial Cells
por: Palkovicsné Pézsa, Nikolett, et al.
Publicado: (2023)

Diagnosis of osteoporosis in statin-treated patients is dose-dependent
por: Leutner, Michael, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_05iibsvl9bs6rfgvg03j5qrosv