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Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
Many pancreatic transcription factors that are essential for islet cell differentiation have been well characterized; however, because they are often expressed in several different cell populations, their functional hierarchy remains unclear. To parse out the spatiotemporal regulation of islet cell...
Autores principales: | Churchill, Angela J, Gutiérrez, Giselle Dominguez, Singer, Ruth A, Lorberbaum, David S, Fischer, Kevin A, Sussel, Lori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224921/ https://www.ncbi.nlm.nih.gov/pubmed/28071588 http://dx.doi.org/10.7554/eLife.20010 |
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