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D19S Mutation of the Cationic, Cysteine-Rich Protein PAF: Novel Insights into Its Structural Dynamics, Thermal Unfolding and Antifungal Function
The cysteine-rich, cationic, antifungal protein PAF is abundantly secreted into the culture supernatant of the filamentous Ascomycete Penicillium chrysogenum. The five β-strands of PAF form a compact β-barrel that is stabilized by three disulphide bonds. The folding of PAF allows the formation of fo...
Autores principales: | Sonderegger, Christoph, Fizil, Ádám, Burtscher, Laura, Hajdu, Dorottya, Muñoz, Alberto, Gáspári, Zoltán, Read, Nick D., Batta, Gyula, Marx, Florentine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224997/ https://www.ncbi.nlm.nih.gov/pubmed/28072824 http://dx.doi.org/10.1371/journal.pone.0169920 |
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