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Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations
Over evolutionary time, members of a superfamily of homologous proteins sharing a common structural core diverge into subgroups filling various functional niches. At the sequence level, such divergence appears as correlations that arise from residue patterns distinct to each subgroup. Such a superfa...
Autores principales: | Neuwald, Andrew F., Altschul, Stephen F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225019/ https://www.ncbi.nlm.nih.gov/pubmed/28002465 http://dx.doi.org/10.1371/journal.pcbi.1005294 |
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