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Cerebral Blood Flow and Aβ-Amyloid Estimates by WARM Analysis of [(11)C]PiB Uptake Distinguish among and between Neurodegenerative Disorders and Aging

Background: We report results of the novel Washout Allometric Reference Method (WARM) that uses estimates of cerebral blood flow and amyloid load from the same [(11)C]Pittsburgh Compound B ([(11)C]PiB) retention maps in brain to distinguish between patients with different forms dementia, including A...

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Detalles Bibliográficos
Autores principales: Rodell, Anders B., O’Keefe, Graeme, Rowe, Christopher C., Villemagne, Victor L., Gjedde, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225115/
https://www.ncbi.nlm.nih.gov/pubmed/28123366
http://dx.doi.org/10.3389/fnagi.2016.00321