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Different Pathways Leading to Integrase Inhibitors Resistance

Integrase strand-transfer inhibitors (INSTIs), such as raltegravir (RAL), elvitegravir, or dolutegravir (DTG), are efficient antiretroviral agents used in HIV treatment in order to inhibit retroviral integration. By contrast to RAL treatments leading to well-identified mutation resistance pathways a...

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Detalles Bibliográficos
Autores principales: Thierry, Eloïse, Deprez, Eric, Delelis, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225119/
https://www.ncbi.nlm.nih.gov/pubmed/28123383
http://dx.doi.org/10.3389/fmicb.2016.02165