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The anterior midcingulate cortex as a neural node underlying hostility in young adults
Anger typically manifests for only a short period of time, whereas hostility is present for a longer duration. However, both of these emotions are associated with an increased likelihood of psychological problems. The nodes within the neural networks that underlie hostility remain unclear. We presum...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225167/ https://www.ncbi.nlm.nih.gov/pubmed/26897177 http://dx.doi.org/10.1007/s00429-016-1200-6 |
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author | Nakagawa, Seishu Takeuchi, Hikaru Taki, Yasuyuki Nouchi, Rui Sekiguchi, Atsushi Kotozaki, Yuka Miyauchi, Carlos Makoto Iizuka, Kunio Yokoyama, Ryoichi Shinada, Takamitsu Yamamoto, Yuki Hanawa, Sugiko Araki, Tsuyoshi Hashizume, Hiroshi Kunitoki, Keiko Sassa, Yuko Kawashima, Ryuta |
author_facet | Nakagawa, Seishu Takeuchi, Hikaru Taki, Yasuyuki Nouchi, Rui Sekiguchi, Atsushi Kotozaki, Yuka Miyauchi, Carlos Makoto Iizuka, Kunio Yokoyama, Ryoichi Shinada, Takamitsu Yamamoto, Yuki Hanawa, Sugiko Araki, Tsuyoshi Hashizume, Hiroshi Kunitoki, Keiko Sassa, Yuko Kawashima, Ryuta |
author_sort | Nakagawa, Seishu |
collection | PubMed |
description | Anger typically manifests for only a short period of time, whereas hostility is present for a longer duration. However, both of these emotions are associated with an increased likelihood of psychological problems. The nodes within the neural networks that underlie hostility remain unclear. We presumed that specific nodes might include the anterior midcingulate cortex (aMCC), which seems to be essential for the cognitive aspects of hostility. Thus, the present study first evaluated the associations between regional gray matter density (rGMD) and hostility in 777 healthy young students (433 men and 344 women; 20.7 ± 1.8 years of age) using magnetic resonance imaging and the hostile behaviors subscale (HBS) of the Coronary-prone Type Scale (CTS) for Japanese populations. The HBS scores were positively correlated with rGMD in the aMCC and in widespread frontal regions from the dorsomedial/dorsolateral prefrontal cortices to the lateral premotor cortex at the whole-brain level. No significant correlation was observed between rGMD and the conjunction of HBS and Trait Anger/Anger-Out scores. Furthermore, no significant interaction effects of sex and HBS scores on rGMD were revealed, although the HBS scores of males were significantly higher than those of females. The present findings indicate that the neural correlates of hostility appear to be more distinct in rGMD than those of anger due to differences and duration. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00429-016-1200-6) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5225167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-52251672017-01-24 The anterior midcingulate cortex as a neural node underlying hostility in young adults Nakagawa, Seishu Takeuchi, Hikaru Taki, Yasuyuki Nouchi, Rui Sekiguchi, Atsushi Kotozaki, Yuka Miyauchi, Carlos Makoto Iizuka, Kunio Yokoyama, Ryoichi Shinada, Takamitsu Yamamoto, Yuki Hanawa, Sugiko Araki, Tsuyoshi Hashizume, Hiroshi Kunitoki, Keiko Sassa, Yuko Kawashima, Ryuta Brain Struct Funct Original Article Anger typically manifests for only a short period of time, whereas hostility is present for a longer duration. However, both of these emotions are associated with an increased likelihood of psychological problems. The nodes within the neural networks that underlie hostility remain unclear. We presumed that specific nodes might include the anterior midcingulate cortex (aMCC), which seems to be essential for the cognitive aspects of hostility. Thus, the present study first evaluated the associations between regional gray matter density (rGMD) and hostility in 777 healthy young students (433 men and 344 women; 20.7 ± 1.8 years of age) using magnetic resonance imaging and the hostile behaviors subscale (HBS) of the Coronary-prone Type Scale (CTS) for Japanese populations. The HBS scores were positively correlated with rGMD in the aMCC and in widespread frontal regions from the dorsomedial/dorsolateral prefrontal cortices to the lateral premotor cortex at the whole-brain level. No significant correlation was observed between rGMD and the conjunction of HBS and Trait Anger/Anger-Out scores. Furthermore, no significant interaction effects of sex and HBS scores on rGMD were revealed, although the HBS scores of males were significantly higher than those of females. The present findings indicate that the neural correlates of hostility appear to be more distinct in rGMD than those of anger due to differences and duration. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00429-016-1200-6) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2016-02-20 2017 /pmc/articles/PMC5225167/ /pubmed/26897177 http://dx.doi.org/10.1007/s00429-016-1200-6 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Article Nakagawa, Seishu Takeuchi, Hikaru Taki, Yasuyuki Nouchi, Rui Sekiguchi, Atsushi Kotozaki, Yuka Miyauchi, Carlos Makoto Iizuka, Kunio Yokoyama, Ryoichi Shinada, Takamitsu Yamamoto, Yuki Hanawa, Sugiko Araki, Tsuyoshi Hashizume, Hiroshi Kunitoki, Keiko Sassa, Yuko Kawashima, Ryuta The anterior midcingulate cortex as a neural node underlying hostility in young adults |
title | The anterior midcingulate cortex as a neural node underlying hostility in young adults |
title_full | The anterior midcingulate cortex as a neural node underlying hostility in young adults |
title_fullStr | The anterior midcingulate cortex as a neural node underlying hostility in young adults |
title_full_unstemmed | The anterior midcingulate cortex as a neural node underlying hostility in young adults |
title_short | The anterior midcingulate cortex as a neural node underlying hostility in young adults |
title_sort | anterior midcingulate cortex as a neural node underlying hostility in young adults |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225167/ https://www.ncbi.nlm.nih.gov/pubmed/26897177 http://dx.doi.org/10.1007/s00429-016-1200-6 |
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