The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China

The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 mon...

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Detalles Bibliográficos
Autores principales: Dian, Ziqin, Fan, Mao, Wang, Binghui, Feng, Yue, Ji, Hao, Dong, Shuwei, Zhang, A-Mei, Liu, Li, Niu, Hua, Xia, Xueshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225225/
https://www.ncbi.nlm.nih.gov/pubmed/27718075
http://dx.doi.org/10.1007/s00705-016-3102-6
Descripción
Sumario:The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-016-3102-6) contains supplementary material, which is available to authorized users.

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