The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China

The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 mon...

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Autores principales: Dian, Ziqin, Fan, Mao, Wang, Binghui, Feng, Yue, Ji, Hao, Dong, Shuwei, Zhang, A-Mei, Liu, Li, Niu, Hua, Xia, Xueshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225225/
https://www.ncbi.nlm.nih.gov/pubmed/27718075
http://dx.doi.org/10.1007/s00705-016-3102-6
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author Dian, Ziqin
Fan, Mao
Wang, Binghui
Feng, Yue
Ji, Hao
Dong, Shuwei
Zhang, A-Mei
Liu, Li
Niu, Hua
Xia, Xueshan
author_facet Dian, Ziqin
Fan, Mao
Wang, Binghui
Feng, Yue
Ji, Hao
Dong, Shuwei
Zhang, A-Mei
Liu, Li
Niu, Hua
Xia, Xueshan
author_sort Dian, Ziqin
collection PubMed
description The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-016-3102-6) contains supplementary material, which is available to authorized users.
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spelling pubmed-52252252017-01-24 The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China Dian, Ziqin Fan, Mao Wang, Binghui Feng, Yue Ji, Hao Dong, Shuwei Zhang, A-Mei Liu, Li Niu, Hua Xia, Xueshan Arch Virol Brief Report The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P[8] (85/107, 79.4 %), which showed high sequence similarity to G9P[8] strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-016-3102-6) contains supplementary material, which is available to authorized users. Springer Vienna 2016-10-07 2017 /pmc/articles/PMC5225225/ /pubmed/27718075 http://dx.doi.org/10.1007/s00705-016-3102-6 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Dian, Ziqin
Fan, Mao
Wang, Binghui
Feng, Yue
Ji, Hao
Dong, Shuwei
Zhang, A-Mei
Liu, Li
Niu, Hua
Xia, Xueshan
The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
title The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
title_full The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
title_fullStr The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
title_full_unstemmed The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
title_short The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
title_sort prevalence and genotype distribution of rotavirus a infection among children with acute gastroenteritis in kunming, china
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225225/
https://www.ncbi.nlm.nih.gov/pubmed/27718075
http://dx.doi.org/10.1007/s00705-016-3102-6
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