Cargando…

Free Light Chains and Intrathecal B Cells Activity in Multiple Sclerosis: A Prospective Study and Meta-Analysis

Background. The presence of CSF oligoclonal bands (OBs) is an independent prognostic factor for multiple sclerosis (MS), but the difficulties in the standardization of the test and the interlaboratory variation in reporting have contributed to its limited use in the diagnosis of the disease. Standar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Passerini, Gabriella, Dalla Costa, Gloria, Sangalli, Francesca, Moiola, Lucia, Colombo, Bruno, Locatelli, Massimo, Comi, Giancarlo, Furlan, Roberto, Martinelli, Vittorio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225376/ https://www.ncbi.nlm.nih.gov/pubmed/28116160 http://dx.doi.org/10.1155/2016/2303857

Ejemplares similares

Prognostic value of serum neurofilaments in patients with clinically isolated syndromes
por: Dalla Costa, Gloria, et al.
Publicado: (2019)

Loss of Circulating CD8+ CD161(high) T Cells in Primary Progressive Multiple Sclerosis
por: Acquaviva, Massimo, et al.
Publicado: (2019)

Inferring Multiple Sclerosis Stages from the Blood Transcriptome via Machine Learning
por: Acquaviva, Massimo, et al.
Publicado: (2020)

The Communication of Multiple Sclerosis Diagnosis: The Patients' Perspective
por: Messina, Maria Josè, et al.
Publicado: (2015)

Intrathecal kappa free light chains as markers for multiple sclerosis
por: Vecchio, D., et al.
Publicado: (2020)

Myeloid cells as target of fingolimod action in multiple sclerosis
por: Di Dario, Marco, et al.
Publicado: (2015)

Changes in cortical motor outputs after a motor relapse of multiple sclerosis
por: Chieffo, Raffaella, et al.
Publicado: (2019)

Dysregulation of MS risk genes and pathways at distinct stages of disease
por: Srinivasan, Sundararajan, et al.
Publicado: (2017)

In vivo structural and functional assessment of optic nerve damage in neuromyelitis optica spectrum disorders and multiple sclerosis
por: Vabanesi, Marco, et al.
Publicado: (2019)

Divergent Trends of Anti-JCPyV Serum Reactivity and Neutralizing Activity in Multiple Sclerosis (MS) Patients during Treatment with Natalizumab
por: Diotti, Roberta Antonia, et al.
Publicado: (2016)

Intrathecal kappa free light chain synthesis is associated with worse prognosis in relapsing–remitting multiple sclerosis
por: Rosenstein, Igal, et al.
Publicado: (2023)

Combining Clinical and Genetic Data to Predict Response to Fingolimod Treatment in Relapsing Remitting Multiple Sclerosis Patients: A Precision Medicine Approach
por: Ferrè, Laura, et al.
Publicado: (2023)

Stress related to COVID-19 pandemic as a trigger for disease activity in multiple sclerosis: a case report
por: Giordano, Antonino, et al.
Publicado: (2021)

Diagnostic accuracy of intrathecal kappa free light chains compared with OCBs in MS
por: Duell, Frida, et al.
Publicado: (2020)

Effectiveness and safety profile of cladribine in an Italian real-life cohort of relapsing–remitting multiple sclerosis patients: a monocentric longitudinal observational study
por: Zanetta, Chiara, et al.
Publicado: (2023)

Correction to: Effectiveness and safety profile of cladribine in an Italian real-life cohort of relapsing–remitting multiple sclerosis patients: a monocentric longitudinal observational study
por: Zanetta, Chiara, et al.
Publicado: (2023)

High frequency of intestinal T(H)17 cells correlates with microbiota alterations and disease activity in multiple sclerosis
por: Cosorich, Ilaria, et al.
Publicado: (2017)

T Regulatory Cells Are Markers of Disease Activity in Multiple Sclerosis Patients
por: Dalla Libera, Dacia, et al.
Publicado: (2011)

Decreased Intrathecal Concentrations of Free Light Chains Kappa in Multiple Sclerosis Patients Taking Very High Effective Disease-Modifying Treatment
por: Süße, Marie, et al.
Publicado: (2022)

Reiber’s Diagram for Kappa Free Light Chains: The New Standard for Assessing Intrathecal Synthesis?
por: Schwenkenbecher, Philipp, et al.
Publicado: (2019)

MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis
por: Lecca, Davide, et al.
Publicado: (2016)

Risk HLA Variants Affect the T-Cell Repertoire in Multiple Sclerosis
por: Sorosina, Melissa, et al.
Publicado: (2023)

Successful treatment of HIV-associated tumefactive demyelinating lesions with corticosteroids and cyclophosphamide: a case report
por: Lazzarin, Serena Marita, et al.
Publicado: (2020)

The Danger of Walking with Socks: Evidence from Kinematic Analysis in People with Progressive Multiple Sclerosis
por: Huang, Su-Chun, et al.
Publicado: (2020)

Intensive Neurorehabilitation and Gait Improvement in Progressive Multiple Sclerosis: Clinical, Kinematic and Electromyographic Analysis
por: Huang, Su-Chun, et al.
Publicado: (2022)

Assessment of Intrathecal Free Light Chain Synthesis: Comparison of Different Quantitative Methods with the Detection of Oligoclonal Free Light Chains by Isoelectric Focusing and Affinity-Mediated Immunoblotting
por: Zeman, David, et al.
Publicado: (2016)

Vaccination Opportunities in Multiple Sclerosis Patients Treated with Cladribine Tablets
por: Moiola, Lucia, et al.
Publicado: (2022)

Impact of MS genetic loci on familial aggregation, clinical phenotype, and disease prediction
por: Esposito, Federica, et al.
Publicado: (2015)

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis
por: Srinivasan, Sundararajan, et al.
Publicado: (2017)

The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes
por: Bertram, Dominic, et al.
Publicado: (2023)

Prognostic factors related to the risk of COVID-19 infection in MS patients
por: Montini, Federico, et al.
Publicado: (2021)

CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort
por: Senel, Makbule, et al.
Publicado: (2019)

High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis
por: Castillo-Villalba, Jéssica, et al.
Publicado: (2022)

Modifiable risk factors of COVID-19 in patients with multiple sclerosis: a single-centre case–control study
por: Montini, Federico, et al.
Publicado: (2023)

Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis
por: Srinivasan, Sundararajan, et al.
Publicado: (2018)

Blood neurofilament light chain and total tau levels at admission predict death in COVID-19 patients
por: De Lorenzo , Rebecca, et al.
Publicado: (2021)

Evidence for an Intrathecal Immunoglobulin Synthesis by Kappa Free Light Chains in Neurological Patients with an Isolated Band in Isoelectric Focusing
por: Weiss, Bastian, et al.
Publicado: (2022)

Atrioventricular block after fingolimod resumption: a consequence of sphingosine-1-phosphate axis alteration due to COVID-19?
por: Orrico, Mario, et al.
Publicado: (2021)

Intrathecal Inflammation in Progressive Multiple Sclerosis
por: Monaco, Salvatore, et al.
Publicado: (2020)

COVID-19 with no antibody response in a multiple sclerosis patient treated with cladribine: Implication for vaccination program?
por: Gelibter, Stefano, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d535fjdf5f399hqltda14iqev0