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The APC/C Coordinates Retinal Differentiation with G1 Arrest through the Nek2-Dependent Modulation of Wingless Signaling

The cell cycle is coordinated with differentiation during animal development. Here we report a cell-cycle-independent developmental role for a master cell-cycle regulator, the anaphase-promoting complex or cyclosome (APC/C), in the regulation of cell fate through modulation of Wingless (Wg) signalin...

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Detalles Bibliográficos
Autores principales: Martins, Torcato, Meghini, Francesco, Florio, Francesca, Kimata, Yuu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225405/
https://www.ncbi.nlm.nih.gov/pubmed/28041905
http://dx.doi.org/10.1016/j.devcel.2016.12.005