The “curved lead pathway” method to enable a single lead to reach any two intracranial targets

Deep brain stimulation is an effective way to treat movement disorders, and a powerful research tool for exploring brain functions. This report proposes a “curved lead pathway” method for lead implantation, such that a single lead can reach in sequence to any two intracranial targets. A new type of...

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Autores principales: Ding, Chen-Yu, Yu, Liang-hong, Lin, Yuan-Xiang, Chen, Fan, Lin, Zhang-Ya, Kang, De-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225435/
https://www.ncbi.nlm.nih.gov/pubmed/28074898
http://dx.doi.org/10.1038/srep40533
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author Ding, Chen-Yu
Yu, Liang-hong
Lin, Yuan-Xiang
Chen, Fan
Lin, Zhang-Ya
Kang, De-Zhi
author_facet Ding, Chen-Yu
Yu, Liang-hong
Lin, Yuan-Xiang
Chen, Fan
Lin, Zhang-Ya
Kang, De-Zhi
author_sort Ding, Chen-Yu
collection PubMed
description Deep brain stimulation is an effective way to treat movement disorders, and a powerful research tool for exploring brain functions. This report proposes a “curved lead pathway” method for lead implantation, such that a single lead can reach in sequence to any two intracranial targets. A new type of stereotaxic system for implanting a curved lead to the brain of human/primates was designed, the auxiliary device needed for this method to be used in rat/mouse was fabricated and verified in rat, and the Excel algorithm used for automatically calculating the necessary parameters was implemented. This “curved lead pathway” method of lead implantation may complement the current method, make lead implantation for multiple targets more convenient, and expand the experimental techniques of brain function research.
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spelling pubmed-52254352017-01-17 The “curved lead pathway” method to enable a single lead to reach any two intracranial targets Ding, Chen-Yu Yu, Liang-hong Lin, Yuan-Xiang Chen, Fan Lin, Zhang-Ya Kang, De-Zhi Sci Rep Article Deep brain stimulation is an effective way to treat movement disorders, and a powerful research tool for exploring brain functions. This report proposes a “curved lead pathway” method for lead implantation, such that a single lead can reach in sequence to any two intracranial targets. A new type of stereotaxic system for implanting a curved lead to the brain of human/primates was designed, the auxiliary device needed for this method to be used in rat/mouse was fabricated and verified in rat, and the Excel algorithm used for automatically calculating the necessary parameters was implemented. This “curved lead pathway” method of lead implantation may complement the current method, make lead implantation for multiple targets more convenient, and expand the experimental techniques of brain function research. Nature Publishing Group 2017-01-11 /pmc/articles/PMC5225435/ /pubmed/28074898 http://dx.doi.org/10.1038/srep40533 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Ding, Chen-Yu
Yu, Liang-hong
Lin, Yuan-Xiang
Chen, Fan
Lin, Zhang-Ya
Kang, De-Zhi
The “curved lead pathway” method to enable a single lead to reach any two intracranial targets
title The “curved lead pathway” method to enable a single lead to reach any two intracranial targets
title_full The “curved lead pathway” method to enable a single lead to reach any two intracranial targets
title_fullStr The “curved lead pathway” method to enable a single lead to reach any two intracranial targets
title_full_unstemmed The “curved lead pathway” method to enable a single lead to reach any two intracranial targets
title_short The “curved lead pathway” method to enable a single lead to reach any two intracranial targets
title_sort “curved lead pathway” method to enable a single lead to reach any two intracranial targets
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225435/
https://www.ncbi.nlm.nih.gov/pubmed/28074898
http://dx.doi.org/10.1038/srep40533
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