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Granulocyte colony-stimulating factor (G-CSF) promotes spermatogenic regeneration from surviving spermatogonia after high-dose alkylating chemotherapy

BACKGROUND: The lifesaving chemotherapy and radiation treatments that allow patients to survive cancer can also result in a lifetime of side-effects, including male infertility. Infertility in male cancer survivors is thought to primarily result from killing of the spermatogonial stem cells (SSCs) r...

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Detalles Bibliográficos
Autores principales: Kotzur, Travis, Benavides-Garcia, Roberto, Mecklenburg, Jennifer, Sanchez, Jamila R., Reilly, Matthew, Hermann, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225630/
https://www.ncbi.nlm.nih.gov/pubmed/28077131
http://dx.doi.org/10.1186/s12958-016-0226-1