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Indatuximab ravtansine (BT062) combination treatment in multiple myeloma: pre-clinical studies
Indatuximab ravtansine is a monoclonal antibody-linked cytotoxic agent that specifically targets CD138-expressing cells. Monotherapy has been shown to significantly inhibit multiple myeloma tumour growth in vivo and improve host survival. Here, we show that in most cell lines tested, indatuximab rav...
Autores principales: | Schönfeld, Kurt, Zuber, Chantal, Pinkas, Jan, Häder, Thomas, Bernöster, Katrin, Uherek, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225632/ https://www.ncbi.nlm.nih.gov/pubmed/28077160 http://dx.doi.org/10.1186/s13045-016-0380-0 |
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