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Indatuximab ravtansine (BT062) combination treatment in multiple myeloma: pre-clinical studies

Indatuximab ravtansine is a monoclonal antibody-linked cytotoxic agent that specifically targets CD138-expressing cells. Monotherapy has been shown to significantly inhibit multiple myeloma tumour growth in vivo and improve host survival. Here, we show that in most cell lines tested, indatuximab rav...

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Detalles Bibliográficos
Autores principales: Schönfeld, Kurt, Zuber, Chantal, Pinkas, Jan, Häder, Thomas, Bernöster, Katrin, Uherek, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225632/
https://www.ncbi.nlm.nih.gov/pubmed/28077160
http://dx.doi.org/10.1186/s13045-016-0380-0

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