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Threonine(175), a novel pathological phosphorylation site on tau protein linked to multiple tauopathies

Microtubule associated protein tau (tau) deposition is associated with a spectrum of neurodegenerative diseases collectively termed tauopathies. We have previously shown that amyotrophic lateral sclerosis (ALS) with cognitive impairment (ALSci) is associated with tau phosphorylation at Thr(175) and...

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Detalles Bibliográficos
Autores principales: Moszczynski, Alexander J., Yang, Wencheng, Hammond, Robert, Ang, Lee Cyn, Strong, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225652/
https://www.ncbi.nlm.nih.gov/pubmed/28077166
http://dx.doi.org/10.1186/s40478-016-0406-4