Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea

Sarcoidosis is a chronic and systemic disorder characterized by the formation of non-caseating granulomas. Very few cases of isolated gastrointestinal sarcoidosis have been reported, and even fewer, if any, report gastrointestinal sarcoidosis within multiple gastrointestinal sites concomitantly. We...

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Autores principales: Stemboroski, Lauren, Gaye, Bilkisu, Makary, Raafat, Monteiro, Carmela, Eid, Emely
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226203/
https://www.ncbi.nlm.nih.gov/pubmed/28119949
http://dx.doi.org/10.14309/crj.2016.171
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author Stemboroski, Lauren
Gaye, Bilkisu
Makary, Raafat
Monteiro, Carmela
Eid, Emely
author_facet Stemboroski, Lauren
Gaye, Bilkisu
Makary, Raafat
Monteiro, Carmela
Eid, Emely
author_sort Stemboroski, Lauren
collection PubMed
description Sarcoidosis is a chronic and systemic disorder characterized by the formation of non-caseating granulomas. Very few cases of isolated gastrointestinal sarcoidosis have been reported, and even fewer, if any, report gastrointestinal sarcoidosis within multiple gastrointestinal sites concomitantly. We present a 42-year-old white man with chronic diarrhea and abdominal pain for more than 3 years. Mucosal biopsies revealed non-caseating microgranulomas in the stomach, throughout the small intestine, colon, and rectum. Prednisone therapy was initiated with a rapid improvement in symptoms and complete resolution of diarrhea within 3 weeks.
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spelling pubmed-52262032017-01-24 Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea Stemboroski, Lauren Gaye, Bilkisu Makary, Raafat Monteiro, Carmela Eid, Emely ACG Case Rep J Case Report Sarcoidosis is a chronic and systemic disorder characterized by the formation of non-caseating granulomas. Very few cases of isolated gastrointestinal sarcoidosis have been reported, and even fewer, if any, report gastrointestinal sarcoidosis within multiple gastrointestinal sites concomitantly. We present a 42-year-old white man with chronic diarrhea and abdominal pain for more than 3 years. Mucosal biopsies revealed non-caseating microgranulomas in the stomach, throughout the small intestine, colon, and rectum. Prednisone therapy was initiated with a rapid improvement in symptoms and complete resolution of diarrhea within 3 weeks. American College of Gastroenterology 2016-12-21 /pmc/articles/PMC5226203/ /pubmed/28119949 http://dx.doi.org/10.14309/crj.2016.171 Text en Copyright © Stemboroski et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Stemboroski, Lauren
Gaye, Bilkisu
Makary, Raafat
Monteiro, Carmela
Eid, Emely
Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea
title Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea
title_full Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea
title_fullStr Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea
title_full_unstemmed Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea
title_short Isolated Gastrointestinal Sarcoidosis Involving Multiple Gastrointestinal Sites Presenting as Chronic Diarrhea
title_sort isolated gastrointestinal sarcoidosis involving multiple gastrointestinal sites presenting as chronic diarrhea
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226203/
https://www.ncbi.nlm.nih.gov/pubmed/28119949
http://dx.doi.org/10.14309/crj.2016.171
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