Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure

Interleukin-15 (IL-15) is a cell growth-factor that regulates lymphocyte function and homeostasis. Its strong immunostimulatory activity coupled with an apparent lack of toxicity makes IL-15 an exciting candidate for cancer therapy, somehow limited by its short half-life in circulation. To increase...

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Detalles Bibliográficos
Autores principales: Scala, Marianna Di, Gil-Fariña, Irene, Olagüe, Cristina, Vales, Africa, Sobrevals, Luciano, Fortes, Puri, Corbacho, David, González-Aseguinolaza, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226487/
https://www.ncbi.nlm.nih.gov/pubmed/27356750
http://dx.doi.org/10.18632/oncotarget.10264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226487/
https://www.ncbi.nlm.nih.gov/pubmed/27356750
http://dx.doi.org/10.18632/oncotarget.10264

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