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Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure

Interleukin-15 (IL-15) is a cell growth-factor that regulates lymphocyte function and homeostasis. Its strong immunostimulatory activity coupled with an apparent lack of toxicity makes IL-15 an exciting candidate for cancer therapy, somehow limited by its short half-life in circulation. To increase...

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Detalles Bibliográficos
Autores principales:	Scala, Marianna Di, Gil-Fariña, Irene, Olagüe, Cristina, Vales, Africa, Sobrevals, Luciano, Fortes, Puri, Corbacho, David, González-Aseguinolaza, Gloria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226487/ https://www.ncbi.nlm.nih.gov/pubmed/27356750 http://dx.doi.org/10.18632/oncotarget.10264

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