Cargando…

Vitamin D(3) suppresses morphological evolution of the cribriform cancerous phenotype

Development of cribriform morphology (CM) heralds malignant change in human colon but lack of mechanistic understanding hampers preventive therapy. This study investigated CM pathobiology in three-dimensional (3D) Caco-2 culture models of colorectal glandular architecture, assessed translational rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Deevi, Ravi K., McClements, Jane, McCloskey, Karen D., Fatehullah, Aliya, Tkocz, Dorota, Javadi, Arman, Higginson, Robyn, Durban, Victoria Marsh, Jansen, Marnix, Clarke, Alan, Loughrey, Maurice B., Campbell, Frederick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226489/
https://www.ncbi.nlm.nih.gov/pubmed/27119498
http://dx.doi.org/10.18632/oncotarget.8863

Ejemplares similares