Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF

The adaptor protein Mig-6 is a negative regulator of EGF signaling. It is shown that Mig-6 inhibits cell migration via direct interaction with the ErbB receptors, thereby inhibiting cross-phosphorylation or targeting the receptors for degradation. Mig-6 has also been shown to bind to and inhibit the...

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Detalles Bibliográficos
Autores principales: Jiang, Xinni, Niu, MengMeng, Chen, Deshi, Chen, Jing, Cao, Yang, Li, Xiaorong, Ying, Haoqiang, Bergholz, Johann, Zhang, Yujun, Xiao, Zhi-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226500/
https://www.ncbi.nlm.nih.gov/pubmed/27341132
http://dx.doi.org/10.18632/oncotarget.10205

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