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Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks

Phosphorylation of histone H2AX on serine 139 (γH2AX) is an early step in cellular response to a DNA double-strand break (DSB). γH2AX foci are generally regarded as markers of DSBs. A growing body of evidence demonstrates, however, that while induction of DSBs always brings about phosphorylation of...

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Detalles Bibliográficos
Autores principales: Rybak, Paulina, Hoang, Agnieszka, Bujnowicz, Lukasz, Bernas, Tytus, Berniak, Krzysztof, Zarębski, Mirosław, Darzynkiewicz, Zbigniew, Dobrucki, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226530/
https://www.ncbi.nlm.nih.gov/pubmed/27391338
http://dx.doi.org/10.18632/oncotarget.10411