Cargando…

P2×7 targeting inhibits growth of human mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive tumor refractory to anti-blastic therapy. MPM cells show several genetic and biochemical defects, e.g. overexpression of oncogenes, downregulation of onco-suppressor genes, dysregulation of microRNA, or alteration of intracellular Ca(2+) homeosta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amoroso, Francesca, Salaro, Erica, Falzoni, Simonetta, Chiozzi, Paola, Giuliani, Anna Lisa, Cavallesco, Giorgio, Maniscalco, Pio, Puozzo, Andrea, Bononi, Ilaria, Martini, Fernanda, Tognon, Mauro, Virgilio, Francesco Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226537/ https://www.ncbi.nlm.nih.gov/pubmed/27391069 http://dx.doi.org/10.18632/oncotarget.10430

Ejemplares similares

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition
por: Patergnani, Simone, et al.
Publicado: (2015)

Metformin Induces Apoptosis and Inhibits Notch1 in Malignant Pleural Mesothelioma Cells
por: Rossini, Marika, et al.
Publicado: (2021)

New Perspectives on Diagnosis and Therapy of Malignant Pleural Mesothelioma
por: Rossini, Marika, et al.
Publicado: (2018)

Circulating microRNAs found dysregulated in ex-exposed asbestos workers and pleural mesothelioma patients as potential new biomarkers
por: Bononi, Ilaria, et al.
Publicado: (2016)

Specific IgG Antibodies React to Mimotopes of BK Polyomavirus, a Small DNA Tumor Virus, in Healthy Adult Sera
por: Pietrobon, Silvia, et al.
Publicado: (2017)

Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine
por: Chiozzi, Paola, et al.
Publicado: (2019)

Purinergic Modulation of Interleukin-1β Release from Microglial Cells Stimulated with Bacterial Endotoxin
por: Ferrari, Davide, et al.
Publicado: (1997)

Sera from Patients with Malignant Pleural Mesothelioma Tested Positive for IgG Antibodies against SV40 Large T Antigen: The Viral Oncoprotein
por: Mazzoni, Elisa, et al.
Publicado: (2022)

Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death
por: Salaro, Erica, et al.
Publicado: (2016)

The P2X7 Receptor-Interleukin-1 Liaison
por: Giuliani, Anna Lisa, et al.
Publicado: (2017)

Association Between Simian Virus 40 and Human Tumors
por: Rotondo, John Charles, et al.
Publicado: (2019)

The Coming of Age of the P2X7 Receptor in Diagnostic Medicine
por: Di Virgilio, Francesco, et al.
Publicado: (2023)

Spontaneous Cell Fusion in Macrophage Cultures Expressing High Levels of the P2Z/P2X(7) Receptor
por: Chiozzi, Paola, et al.
Publicado: (1997)

Epigenetic investigation into circulating microRNA 197-3p in sera from patients affected by malignant pleural mesothelioma and workers ex-exposed to asbestos
por: Di Mauro, Giulia, et al.
Publicado: (2023)

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth
por: Bergamin, Letícia Scussel, et al.
Publicado: (2019)

New Insights into Molecular Oncogenesis and Therapy of Uveal Melanoma
por: Violanti, Sara Silvia, et al.
Publicado: (2019)

Specific Detection of Serum Antibodies against BKPyV, A Small DNA Tumour Virus, in Patients Affected by Choroidal Nevi
por: Pietrobon, Silvia, et al.
Publicado: (2017)

Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation
por: Di Virgilio, Francesco, et al.
Publicado: (2018)

Colorectal Carcinoma Affected Patients Are Significantly Poor Responders Against the Oncogenic JC Polyomavirus
por: Torreggiani, Elena, et al.
Publicado: (2021)

A(3) Adenosine and P2X7 Purinergic Receptors as New Targets for an Innovative Pharmacological Therapy of Malignant Pleural Mesothelioma
por: Vincenzi, Fabrizio, et al.
Publicado: (2021)

The P2X7 receptor is a key modulator of aerobic glycolysis
por: Amoroso, F, et al.
Publicado: (2012)

Extracellular ATP is increased by release of ATP-loaded microparticles triggered by nutrient deprivation
por: Vultaggio-Poma, Valentina, et al.
Publicado: (2022)

Antibodies reacting with Simian Virus 40 capsid protein mimotopes in serum samples from patients affected by uveal melanoma
por: Bononi, Ilaria, et al.
Publicado: (2014)

Serum Antibodies Against Simian Virus 40 Large T Antigen, the Viral Oncoprotein, in Osteosarcoma Patients
por: Mazzoni, Elisa, et al.
Publicado: (2018)

Application of Indocyanine Green Enhanced Fluorescence in Esophageal Surgery: A Mini Review
por: Tamburini, Nicola, et al.
Publicado: (2022)

Detection of Merkel Cell Polyomavirus DNA in Serum Samples of Healthy Blood Donors
por: Mazzoni, Elisa, et al.
Publicado: (2017)

Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas
por: Oton-Gonzalez, Lucia, et al.
Publicado: (2021)

Circulating microRNA-197-3p as a potential biomarker for asbestos exposure
por: Frontini, Francesca, et al.
Publicado: (2021)

The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies
por: Iaquinta, Maria Rosa, et al.
Publicado: (2021)

Detecting adenosine triphosphate in the pericellular space
por: Falzoni, Simonetta, et al.
Publicado: (2013)

Adult Stem Cells for Bone Regeneration and Repair
por: Iaquinta, Maria Rosa, et al.
Publicado: (2019)

Association of Hypomorphic P2X7 Receptor Genotype With Age
por: Sanz, Juana Maria, et al.
Publicado: (2020)

Possible protective role of the 489C>T P2X7R polymorphism in Alzheimer's disease
por: Sanz, Juana M., et al.
Publicado: (2014)

Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus
por: Bononi, Ilaria, et al.
Publicado: (2022)

Antioxidant Activity of Resveratrol Diastereomeric Forms Assayed in Fluorescent-Engineered Human Keratinocytes
por: Bononi, Ilaria, et al.
Publicado: (2022)

MicroRNAs Modulate Signaling Pathways in Osteogenic Differentiation of Mesenchymal Stem Cells
por: Mazziotta, Chiara, et al.
Publicado: (2021)

Specific Antibodies Reacting with SV40 Large T Antigen Mimotopes in Serum Samples of Healthy Subjects
por: Tognon, Mauro, et al.
Publicado: (2016)

Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel (18)F-labelled PET tracer targeting P2X7
por: Fantoni, Enrico Raffaele, et al.
Publicado: (2017)

Factors Associated with Early Discharge after Thoracoscopic Lobectomy: Results from the Italian VATS Group Registry
por: Maniscalco, Pio, et al.
Publicado: (2022)

NLRP1 polymorphisms in patients with asbestos-associated mesothelioma
por: Girardelli, Martina, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_mf15aaqj0535josrp5u3d4e8uc