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Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes
Connexin43 (Cx43), the major protein forming gap junctions in astrocytes, is reduced in high-grade gliomas, where its ectopic expression exerts important effects, including the inhibition of the proto-oncogene tyrosine-protein kinase Src (c-Src). In this work we aimed to investigate the mechanism re...
Autores principales: | González-Sánchez, Ana, Jaraíz-Rodríguez, Myriam, Domínguez-Prieto, Marta, Herrero-González, Sandra, Medina, José M., Tabernero, Arantxa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226550/ https://www.ncbi.nlm.nih.gov/pubmed/27391443 http://dx.doi.org/10.18632/oncotarget.10454 |
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