The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer

Tumor cells develop drug resistance which leads to recurrence and distant metastasis. MicroRNAs are key regulators of tumor pathogenesis; however, little is known whether they can sensitize cells and block metastasis simultaneously. Here, we report miR-644a as a novel inhibitor of both cell survival...

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Detalles Bibliográficos
Autores principales: Raza, Umar, Saatci, Özge, Uhlmann, Stefan, Ansari, Suhail A, Eyüpoğlu, Erol, Yurdusev, Emre, Mutlu, Merve, Ersan, Pelin Gülizar, Altundağ, Mustafa Kadri, Zhang, Jitao David, Doğan, Hayriye Tatlı, Güler, Gülnur, Şahin, Özgür
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226553/
https://www.ncbi.nlm.nih.gov/pubmed/27409664
http://dx.doi.org/10.18632/oncotarget.10489

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