Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC cells. Here we found that treatment of high-grade...

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Detalles Bibliográficos
Autores principales: Amantini, Consuelo, Morelli, Maria Beatrice, Nabissi, Massimo, Cardinali, Claudio, Santoni, Matteo, Gismondi, Angela, Santoni, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226576/
https://www.ncbi.nlm.nih.gov/pubmed/27367032
http://dx.doi.org/10.18632/oncotarget.10326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226576/
https://www.ncbi.nlm.nih.gov/pubmed/27367032
http://dx.doi.org/10.18632/oncotarget.10326

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