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5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53

Recent findings revealed in cancer cells novel stress response pathways, which in response to many chemotherapeutic drugs causing nucleolar stress, will function independently from tumor protein p53 (p53) and still lead to cell cycle arrest and/or apoptosis. Since it is known that most cancers lack...

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Detalles Bibliográficos
Autores principales:	Pagliara, Valentina, Saide, Assunta, Mitidieri, Emma, Roberta d'Emmanuele di Villa, Bianca, Sorrentino, Raffaella, Russo, Giulia, Russo, Annapina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226586/ https://www.ncbi.nlm.nih.gov/pubmed/27385096 http://dx.doi.org/10.18632/oncotarget.10385

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