A novel pathogenic large germline deletion in adenomatous polyposis coli gene in a Chinese family with familial adenomatous polyposis

Germline mutations of the APC gene are associated with an autosomal dominant precancerous condition, termed familial adenomatous polyposis (FAP). FAP is clinically manifested by the presence of multiple colorectal adenomas or polyps. Gradually, these colorectal adenomas or polyps inevitably result i...

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Detalles Bibliográficos
Autores principales: Zhang, Zhao, Liang, Shengran, Huang, Hui, Wang, Dan, Zhang, Xipeng, Wu, Jing, Chen, Huishuang, Wang, Yanyan, Rong, Tingting, Zhou, Yulin, Banerjee, Santasree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226590/
https://www.ncbi.nlm.nih.gov/pubmed/27391059
http://dx.doi.org/10.18632/oncotarget.10408

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