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Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer
BACKGROUND: Notch pathway plays a complex role depending on cellular contexts: promotes stem cell maintenance or induces terminal differentiation in potential cancer-initiating cells; acts as an oncogene in lymphocytes and mammary tissue or plays a growth-suppressive role in leukemia, liver, skin, a...
Autores principales: | Upadhyay, Pawan, Nair, Sudhir, Kaur, Ekjot, Aich, Jyotirmoi, Dani, Prachi, Sethunath, Vidyalakshmi, Gardi, Nilesh, Chandrani, Pratik, Godbole, Mukul, Sonawane, Kavita, Prasad, Ratnam, Kannan, Sadhana, Agarwal, Beamon, Kane, Shubhada, Gupta, Sudeep, Dutt, Shilpee, Dutt, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226594/ https://www.ncbi.nlm.nih.gov/pubmed/27391340 http://dx.doi.org/10.18632/oncotarget.10419 |
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