Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology

Activating and resistance mutations in the tyrosine kinase domain of several oncogenes are frequently associated with non-small cell lung carcinoma (NSCLC). In this study we assessed the frequency, type and abundance of EGFR, KRAS, BRAF, TP53 and ALK mutations in tumour specimens from 184 patients w...

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Detalles Bibliográficos
Autores principales: Zhang, Shirong, Xia, Bing, Jiang, Hong, Wang, Limin, Xu, Rujun, Shi, Yanbin, Zhang, Jianguang, Xu, Mengnan, Cram, David S., Ma, Shenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226597/
https://www.ncbi.nlm.nih.gov/pubmed/27409166
http://dx.doi.org/10.18632/oncotarget.10464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226597/
https://www.ncbi.nlm.nih.gov/pubmed/27409166
http://dx.doi.org/10.18632/oncotarget.10464

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