Cargando…

Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology

Activating and resistance mutations in the tyrosine kinase domain of several oncogenes are frequently associated with non-small cell lung carcinoma (NSCLC). In this study we assessed the frequency, type and abundance of EGFR, KRAS, BRAF, TP53 and ALK mutations in tumour specimens from 184 patients w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shirong, Xia, Bing, Jiang, Hong, Wang, Limin, Xu, Rujun, Shi, Yanbin, Zhang, Jianguang, Xu, Mengnan, Cram, David S., Ma, Shenglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226597/ https://www.ncbi.nlm.nih.gov/pubmed/27409166 http://dx.doi.org/10.18632/oncotarget.10464

Ejemplares similares

Increased MIR31HG lncRNA expression increases gefitinib resistance in non-small cell lung cancer cell lines through the EGFR/PI3K/AKT signaling pathway
por: Wang, Bing, et al.
Publicado: (2017)

Amplification of Cellular Oncogenes in Solid Tumors
por: Bagci, Ozkan, et al.
Publicado: (2015)

Extrachromosomal oncogene amplification drives tumor evolution and genetic heterogeneity
por: Turner, Kristen M., et al.
Publicado: (2017)

Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification
por: Kornegoor, Robert, et al.
Publicado: (2012)

CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules
por: Feng, Wei, et al.
Publicado: (2021)

A comprehensive multiplex PCR based exome-sequencing assay for rapid bloodspot confirmation of inborn errors of metabolism
por: Wang, Wenjie, et al.
Publicado: (2019)

Identification of somatic copy number variations in plasma cell free DNA correlating with intrinsic resistances to EGFR targeted therapy in T790M negative non-small cell lung cancer
por: Zhu, Lucheng, et al.
Publicado: (2020)

Suberoylanilide hydroxamic acid enhances the radiosensitivity of lung cancer cells through acetylated wild-type and mutant p53-dependent modulation of mitochondrial apoptosis
por: Wu, Kan, et al.
Publicado: (2021)

Targeting MET Amplification as a New Oncogenic Driver
por: Kawakami, Hisato, et al.
Publicado: (2014)

Oncogene Amplification in Squamous Cell Carcinoma of the Oral Cavity
por: Saranath, Dhananjaya, et al.
Publicado: (1989)

Increased Biological Effective Dose of Radiation Correlates with Prolonged Survival of Patients with Limited-Stage Small Cell Lung Cancer: A Systematic Review
por: Zhu, Lucheng, et al.
Publicado: (2016)

Comprehensive Quantitative Analysis of SQ Injection Using Multiple Chromatographic Technologies
por: Chau, Siu-Leung, et al.
Publicado: (2016)

Small Molecules Targeting c-Myc Oncogene: Promising Anti-Cancer Therapeutics
por: Chen, Bing-Jia, et al.
Publicado: (2014)

Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
por: Cai, Shenglin, et al.
Publicado: (2021)

Emerging Transistor Technologies Capable of Terahertz Amplification: A Way to Re-Engineer Terahertz Radar Sensors
por: Božanić, Mladen, et al.
Publicado: (2019)

Re-Configuration of Sphingolipid Metabolism by Oncogenic Transformation
por: Don, Anthony S., et al.
Publicado: (2014)

Amplification and Re-Generation of LNA-Modified Libraries
por: Doessing, Holger, et al.
Publicado: (2012)

HER-2/neu oncogene: what does amplification mean?
por: Pavy, J. J., et al.
Publicado: (1993)

HER2 Oncogene Amplification and Immunohistochemical Profiling in Gastric Adenocarcinoma
por: Raj, Nisha, et al.
Publicado: (2018)

The Comprehensive Analysis of Hub Gene ARRB2 in Prostate Cancer
por: Zhou, Bing, et al.
Publicado: (2022)

Gene amplification system based on double rolling-circle replication as a model for oncogene-type amplification
por: Watanabe, Takaaki, et al.
Publicado: (2011)

Dysregulated Immune and Metabolic Microenvironment Is Associated with the Post-Operative Relapse in Stage I Non-Small Cell Lung Cancer
por: Zhang, Shirong, et al.
Publicado: (2022)

ERα-associated translocations underlie oncogene amplifications in breast cancer
por: Lee, Jake June-Koo, et al.
Publicado: (2023)

Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component
por: Zhang, Shirong, et al.
Publicado: (2021)

Molecular characterization of a novel ring 6 chromosome using next generation sequencing
por: Zhang, Rui, et al.
Publicado: (2016)

Single-Molecule Detection of Nucleic Acids via Liposome Signal Amplification in Mass Spectrometry
por: Lin, Xiangcheng, et al.
Publicado: (2022)

Amplification and Quantitation of Telomeric Extrachromosomal Circles
por: Robinson, Nathaniel J., et al.
Publicado: (2023)

Birth of a child with trisomy 9 mosaicism syndrome associated with paternal isodisomy 9: case of a positive noninvasive prenatal test result unconfirmed by invasive prenatal diagnosis
por: Ma, Jingmei, et al.
Publicado: (2015)

NUPR1 imparts oncogenic potential in bladder cancer
por: Zhang, Lifeng, et al.
Publicado: (2022)

Genome-wide profiling reveals alternative polyadenylation of mRNA in human non-small cell lung cancer
por: Zhang, Shirong, et al.
Publicado: (2019)

Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia
por: Windisch, Roland, et al.
Publicado: (2019)

Strand Invasion Based Amplification (SIBA®): A Novel Isothermal DNA Amplification Technology Demonstrating High Specificity and Sensitivity for a Single Molecule of Target Analyte
por: Hoser, Mark J., et al.
Publicado: (2014)

Glasgow prognostic score predicts prognosis of non-small cell lung cancer: a meta-analysis
por: Zhu, Lucheng, et al.
Publicado: (2016)

Single molecule sequencing of the M13 virus genome without amplification
por: Zhao, Luyang, et al.
Publicado: (2017)

Capilliposide C from Lysimachia capillipes Restores Radiosensitivity in Ionizing Radiation-Resistant Lung Cancer Cells Through Regulation of ERRFI1/EGFR/STAT3 Signaling Pathway
por: Wu, Kan, et al.
Publicado: (2021)

Quantitative Imaging of Bacteriophage Amplification for Rapid Detection of Bacteria in Model Foods
por: Wisuthiphaet, Nicharee, et al.
Publicado: (2022)

Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation
por: Zhang, Shirong, et al.
Publicado: (2015)

Amplification Target ADRM1: Role as an Oncogene and Therapeutic Target for Ovarian Cancer
por: Fejzo, Marlena S., et al.
Publicado: (2013)

Mutation and genomic amplification of the PIK3CA proto-oncogene in pituitary adenomas
por: Murat, C.B., et al.
Publicado: (2012)

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
por: Berenjeno, Inma M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_35or3qqmrqg122gkigrsskt35a