Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics

Cambogin, a bioactive polycyclic polyprenylated acylphoroglucinol (PPAP) derived from the Garcinia genus, possesses proapoptotic effect in medulloblastoma and breast cancer cells. We have previously demonstrated that the proapoptotic effect of cambogin is driven by the production of reactive oxygen...

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Detalles Bibliográficos
Autores principales: Shen, Kaikai, Lu, Fangfang, Xie, Jianling, Wu, Minfeng, Cai, Bo, Liu, Yurong, Zhang, Hong, Tan, Hongsheng, Pan, Yingyi, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226606/
https://www.ncbi.nlm.nih.gov/pubmed/27418140
http://dx.doi.org/10.18632/oncotarget.10585

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