In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice

BACKGROUND: Mosaicism, the presence of genetically distinct cell populations within an organism, has emerged as an important contributor to disease. Mutational events occurring during embryonic development can cause mosaicism in any tissue, but the influence of environmental factors on levels of mos...

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Detalles Bibliográficos
Autores principales: Meier, Matthew J., O’Brien, Jason M., Beal, Marc A., Allan, Beverly, Yauk, Carole L., Marchetti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226697/
https://www.ncbi.nlm.nih.gov/pubmed/27448386
http://dx.doi.org/10.1289/EHP211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226697/
https://www.ncbi.nlm.nih.gov/pubmed/27448386
http://dx.doi.org/10.1289/EHP211

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